Immune checkpoint inhibitor-induced lichenoid drug eruption-sparing scar burns.

Truong K, Chamberlin CV, Kim J, Carlino MS, Araujo RR. Australas J Dermatol, (Nov 27 2023), doi:10.1111/ajd.14192.

Abstract

The authors present a striking case of a patient experiencing a lichenoid drug eruption secondary to immunotherapy, curiously sparing scarred skin from past burns. We observed vastly higher amounts of inflammatory lymphoid cells staining for PD-1; 70% in skin with a lichenoid drug reaction and 50% in scarred skin. The lack of a lichenoid reaction at sites of scarred skin may indicate that a basement membrane component may be causative for a lichenoid drug eruption.