Merkel-cell carcinoma: ESMO-EURACAN Clinical Practice Guideline for diagnosis, treatment and follow-up.

Lugowska I, Becker JC, Ascierto PA, Veness M, Blom A, Lebbe C, Migliano E, Hamming-Vrieze O, Goebeler M, Kneitz H, Nathan P, Rutkowski P, Slowinska M, Schadendorf D, Piulats JM, Petrelli F, van Akkooi ACJ, Berruti A. ESMO Open, (Apr 30 2024), doi:10.1016/j.esmoop.2024.102977.

Abstract

  1. This ESMO Clinical Practice Guideline provides key recommendations for managing Merkel-cell carcinoma (MCC).
  2. Recommendations are based on available scientific data and the multidisciplinary group of experts’ collective opinion.
  3. The guideline covers clinical and pathological diagnosis, staging and risk assessment, treatment and follow-up.
  4. Algorithms for the management of locoregional and inoperable/metastatic disease are provided.
  5. A multidisciplinary team with a high level of expertise in MCC should diagnose and make decisions about therapy.