Professor Richard Scolyer AO

BMedSci MBBS MD FRCPA FRCPath FAHMS

Pathologist

Professor Richard Scolyer AO, BMedSci, MBBS, MD, FRCPA, FRCPath, FAHMS is Senior Staff Specialist, Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Sydney; Faculty Member at Melanoma Institute Australia; and Conjoint Professor, Sydney Medical School, Faculty of Medicine and Health, The University of Sydney.

Richard provides a clinical consultation service for the diagnosis of difficult pigmented lesions and receives more than 2000 cases for opinion from Australasia and beyond annually. Richard effectively integrates his clinical practice with co-leading an award winning translational melanoma research laboratory. His record includes co-authoring more than 800 peer reviewed publications, books and/or book-chapters including in prestigious journals such as New England Journal of Medicine, Lancet, Nature, Cell, Nature Genetics, Lancet Oncology, Journal of Clinical Oncology, Journal of the National Cancer Institute and Cancer Discovery with >63,508 citations and a H-index of 120 (Google Scholar as at 3 August 2022). Richard has presented on more than 400 occasions at conferences throughout the world.

In June 2021, he was appointed Officer of the Order of Australia (AO) for distinguished service to medicine, particularly in the field of melanoma and skin cancer, and to national and international professional organisations by The Governor-General of the Commonwealth of Australia. In January 2024 Professor Scolyer and his colleague Professor Georgina Long were jointly named as 2024 Australians of the Year.

In 2020, Prof Scoyer received the NSW Premier's Award for Outstanding Cancer Researcher of the Year, the Royal College of Pathologists of Australasia (RCPA) Distinguished Fellow Award 2020, The University of Sydney’s 2020 Alumni Award for International Achievement and Clarivate Web of Science Group Highly Cited Researcher in 2018, 2019, 2020 and 2021. Richard has received the NSW Premier's Award for Outstanding Cancer Research in 2009, 2012, 2013, 2014, 2016, 2017, 2018, 2020 and 2021, Thomson Reuters 2015 Citation Award in the Clinical Medicine category, the 2018 William O. Russell/Joanne Vandenberge Hill Award for Lifetime Achievement in Anatomical Pathology from MD Anderson Cancer Center, Research Australia’s 2018 GSK Award for Research Excellence, the 2019 American Society of Dermatopathology’s Elson B Helwig Award for excellence in dermatopathology, the 2021 University of Tasmania Distinguished Alumni Award and the 2021 University of Sydney’s Vice-Chancellor Award for Outstanding Research. In May 2023 Richard received the 2023 Founders' Award from The American Society of Dermatopathology, recognising his outstanding contribution to the field of dermatopathology, and the 2023 Distinguished Pathologist Award from the International Academy of Pathology (IAP) Australasian Division, to honour his enormous contributions to pathology in Australasia and beyond. In November 2023 he received 2023 Lifetime Achievement Award from The Society for Melanoma Research. 

According to Thomson Reuters ISI Web of Knowledge, Richard is the highest ever published scientist in the world in the field of melanoma pathology and he also has the highest H index in this field. The Fame Report (2011) published by Medical Experts International (medexpert.com) ranked him the 6th leading melanoma expert in any field or discipline worldwide and the highest ranked melanoma pathologist worldwide. In June 2022, he was ranked the world’s 6th leading melanoma expert in any field or discipline and the world’s leading melanoma pathologist (expertscape.com). In September 2019, Richard was ranked as the leading Australian Pathologist in the entire field of pathology (leagueofscholars.com).

Richard is an expert member of the World Health Organisation (WHO) Blue Books Editorial Board for the 5th edition of the WHO Classification of Skin Tumours series and was an editor of the 4th Edition of the World Health Organisation Classification of Tumours Skin Tumours volume in which he was the responsible editor for 3 of the 6 sections and authored/co-authored more than 30 chapters.He has also been an invited contributing author to 6 other volumes of the WHO Classification of Tumours including for Soft Tissue and Bone, Digestive System, Thoracic, Female Genital Tract and Paediatric tumours. He is also Vice Chair of the Melanoma Expert Panel of the American Joint Committee on Cancer (AJCC) for the 8ᵗʰ and 9ᵗʰ editions of AJCC Cancer Staging System, co-leads the Australian Melanoma Genome Project (part of the International Cancer Genome Consortium), was lead pathologist for the NIH funded The Cancer Genome Atlas (TCGA) Melanoma Project (Cell, 2015), chairs the Melanoma Expert Panel for the International Collaboration on Cancer Reporting, lead pathologist/member of the overseeing Management Committee, Multidisciplinary Working Party and Author for the Australian Melanoma Clinical Practice Guidelines and co-lead author of the College of American Pathologists Melanoma Reporting protocol. He is Editor-in-Chief of Pathology and is also an editorial board member of the American Journal of Surgical Pathology, Modern Pathology and Histopathology and several other international journals. Richard is a Past President of the Australasian Division of the International Academy of Pathology and is the current International Vice President representing Australasia on the International Academy of Pathology International Council. In 2019, Richard was the RCPA visiting Professor/Lecturer to Asia. Together with other MIA colleagues, Richard has been chief investigator on 3 consecutive 5 year NHMRC program grants (2006-2021) and has received multiple personal Fellowships from the NHMRC and CINSW. He has on multiple phase 1, 2 and 3 clinical trials and a frequently sought-after advisor to industry.

Please join Richard on his journey by following him on social:
Instagram: @profrscolyer

Prof Scolyer Recent News

Prof Scolyer Recent Publications

Correction to: Neoadjuvant Systemic Therapy (NAST) in Patients with Melanoma: Surgical Considerations by the International Neoadjuvant Melanoma Consortium (INMC)

2025-11-10T13:57:52+11:00November 10th, 2025|

van Akkooi ACJ, Hieken TJ, Burton EM, Ariyan C, Ascierto PA, Asero SVMA, Blank CU, Block MS, Boland GM, Caraco C, Chng S, Davidson BS, Duprat Neto JP, Faries MB, Gershenwald JE, Grunhagen DJ, Gyorki DE, Han D, Hayes AJ, van Houdt WJ, Karakousis GC, Klop WMC, Long GV, Lowe MC, Menzies AM, Bagge RO, Pennington TE, Rutkowski P, Saw RPM, Scolyer RA, Shannon KF, Sondak VK, Tawbi H, Testori AAE, Tetzlaff MT, Thompson JF, Zager JS, Zuur CL, Wargo JA, Spillane AJ, Ross MI, International Neoadjuvant Melanoma C. Annals of Surgical Oncology, (Apr 15 2022), doi:10.1245/s10434-022-11622-0. TOP 10%

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Federated deep learning enables cancer subtyping by proteomics.

2025-06-19T15:25:25+10:00May 2nd, 2025|

Cai* Z, Boys* E, Noor* Z, Aref* A, Xavier D, Lucas N, Williams S, Koh J, Poulos R, Wu Y, Dausmann M, MacKenzie K, Aguilar A, Niell C, Barranco M, Basik M, Bowman E, Clifton-Bligh R, Connolly E, Cooper W, Dalal B, De Fazio A, Filipits M, Flynn P, Graham JD, George J, Gill A, Gnant M, Habib R, Harris C, Harvey K, Horvath L, Jackson C, Kohonen-Corish M, Lim E, Long GV, Lord R, Mann GJ, McCaughan G, Morgan L, Murphy L, Nagrial A, Panizza B, Samra J, Scolyer RA, Ioannis Souglakos I, Swarbrick A, Thomas D, Hains* P, Balleine* R, Robinson* P, Zhong* Q, Reddel* R. Cancer Discovery, (Accepted May 02 2025). TOP 10%

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Cartilage Resection in the Surgical Management of Ear Melanoma.

2025-05-29T10:29:48+10:00April 28th, 2025|

Novis E, Tan J, Vignati D, Wong T, Rawson RV, Stretch JR, Lo SN, Pennington TE, Ch’ng S, Shannon KF, Spillane AJ, Nieweg OE, Thompson JF, Rtshiladze M, Scolyer RA, Saw RPM. Annals of Surgical Oncology, (Apr 28 2025), doi:10.1245/s10434-025-17294-w.

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Longitudinal Analysis Reveals Dynamic Changes in Histopathologic Features in Responders to Neoadjuvant Treatment in a Stage III BRAF-Mutant Melanoma Cohort.

2025-05-29T09:54:07+10:00April 14th, 2025|

Braden J, Potter A, Rawson RV, Adegoke NA, Lo SN, Conway JW, Menzies AM, Carlino MS, Au-Yeung G, Saw RPM, Spillane AJ, Shannon KF, Pennington TE, Ch’ng S, Gyorki DE, Howle JR, Wilmott JS, Scolyer RA, Long GV, Pires da Silva I. Modern Pathology, (Apr 14 2025): 100776, doi:https://doi.org/10.1016/j.modpat.2025.100776. TOP 10%

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Global Applicability of a Risk Prediction Tool for Sentinel Node Positivity in Patients With Primary Cutaneous Melanoma.

2025-05-29T10:15:33+10:00April 9th, 2025|

Lo SN, Gjorup C, Chakera AH, Hölmich LR, Moncrieff M, MacKenzie Ross A, Cassell O, Ma J, Weitemeyer MB-M, Bagge RO, Klausen S, Calsavara VF, Duprat Neto JP, Bertolli E, Ch’ng S, Saw RPM, Shannon KF, Spillane AJ, Nieweg OE, Stretch JR, Mann GJ, Geh JLC, Haydu LE, Martin RCW, Sharon C, Karakousis GC, Kashani-Sabet M, Adigbli G, El Sharouni M-A, Gershenwald JE, Scolyer RA, Thompson JF, Varey AHR. JAMA Dermatology, (Apr 09 2025), doi:10.1001/jamadermatol.2025.0318.

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FDG-PET associations with pathological response and survival with neoadjuvant immunotherapy for melanoma.

2025-05-29T11:00:54+10:00March 3rd, 2025|

Zhou L, Barros e Silva MJ, Hsiao E, Eroglu Z, Sandhu S, Samoylenko I, Lo SN, Carlino MS, Au-Yeung G, Gonzalez M, Spillane AJ, Pennington TE, Shannon KF, Kapoor R, Burton EM, Tawbi HA, Amaria RN, Blank CU, Duprat JP, Brito de Paula R, Gyorki DE, Saw RPM, Ch’Ng S, Rawson RV, Scolyer RA, Pires da Silva I, Akkooi ACJv, Long GV, Menzies AM. Journal for ImmunoTherapy of Cancer, 13, no. 3, (Mar 25 2025): e011483, doi:10.1136/jitc-2025-011483.

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Neoadjuvant triplet immune checkpoint blockade in newly diagnosed glioblastoma.

2025-03-27T14:52:54+11:00February 27th, 2025|

Long GV, Shklovskaya E, Satgunaseelan L, Mao Y, da Silva IP, Perry KA, Diefenbach RJ, Gide TN, Shivalingam B, Buckland ME, Gonzalez M, Caixeiro N, Vergara IA, Bai X, Rawson RV, Hsiao E, Palendira U, Phan TG, Menzies AM, Carlino MS, Quek C, Grimmond SM, Vissers JHA, Yeo D, Rasko JEJ, Khasraw M, Neyns B, Reardon DA, Ashley DM, Wheeler H, Back M, Scolyer RA, Drummond J, Wilmott JS, Rizos H. Nature Medicine, (Feb 27 2025), doi:10.1038/s41591-025-03512-1. TOP 1%

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Response to han and liu.

2025-03-27T14:16:10+11:00February 6th, 2025|

Lo SN, Varey AHR, Ch’ng S, Scolyer RA, Thompson JF. J Natl Cancer Inst, (Feb 6 2025), doi:10.1093/jnci/djaf026. TOP 10%

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Multiomic profiling of checkpoint inhibitor-treated melanoma: Identifying predictors of response and resistance, and markers of biological discordance.

2025-04-07T12:33:21+10:00February 6th, 2025|

Newell F, Pires da Silva I, Johansson PA, Menzies AM, Wilmott JS, Addala V, Carlino MS, Rizos H, Nones K, Edwards JJ, Lakis V, Kazakoff SH, Mukhopadhyay P, Ferguson PM, Leonard C, Koufariotis LT, Wood S, Blank CU, Thompson JF, Spillane AJ, Saw RPM, Shannon KF, Pearson JV, Mann GJ, Hayward NK, Scolyer RA, Waddell N, Long GV. Cancer Cell, (Feb 06 2025), doi:https://doi.org/10.1016/j.ccell.2025.01.011. TOP 10%

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Neoadjuvant or perioperative therapy for melanoma metastasis in clinical practice: an international survey.

2025-03-27T13:42:04+11:00January 1st, 2025|

Hauschild A, Garbe C, Ascierto PA, Demidov L, Dreno B, Dummer R, Eggermont A, Forsea A-M, Gebhardt C, Gershenwald JE, Hamid O, Hoeller C, Kandolf L, Kaufmann R, Kirkwood JM, Lebbé C, Long GV, Malvehy J, Martin-Algarra S, McArthur G, Neyns B, Richtig E, Robert C, Schadendorf D, Scolyer R, Sondak VK, Wainstein A, Weichenthal M, Nuti P, Aarts MJB, Arance A, Asher N, Berciano-Guerrero M-A, Berking C, Carlino MS, Dabelić N, Davar D, Espinosa E, Forschner A, Gaide O, Gaudy-Marqueste C, Gavrilova I, Grabbe S, Gutzmer R, Hafner C, Hassel JC, Jacobs C, Jang S, Kähler KC, Kehrer H, Koelblinger P, Leiter U, Lipson EJ, Livingstone E, Luke JJ, Mandalà M, Mangana J, Marić Brozić J, Marquez-Rodas I, Maul LV, Mazilu L, Mehmi I, Meier F, Mesti T, Mitchell TC, Mohr P, Moyers J, Muñoz Couselo E, Najjar YG, Nakamura Y, Ocvirk J, Orlova K, Popescu BC, Popovic A, Posch C, Queirolo P, Ramelyte E, Roberts-Thomson R, Rorive A, Ruhlmann CH, Rutten A, Salama AKS, Samoylenko I, Schilling B, Shalamanova-Deleva G, Siano M, Smithy JW, Stelzhammer P, Suijkerbuijk K, Terheyden P, Teterycz P, Tietze JK, Urbonas V, Utyashev I, van der Veldt AAM, Venter M, Zarour HM, Zimmer L, Zinovev G. The Lancet Oncology, 26, no. 1, (Jan 2025): 12-14, doi:10.1016/S1470-2045(24)00627-2. TOP 10%

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Impact of personalized response-directed surgery and adjuvant therapy on survival after neoadjuvant immunotherapy in stage III melanoma: Comparison of 3-year data from PRADO and OpACIN-neo.

2025-03-27T16:27:55+11:00November 19th, 2024|

Reijers ILM, Menzies AM, Lopez-Yurda M, Versluis JM, Rozeman EA, Saw RPM, van Houdt WJ, Kapiteijn E, van der Veldt AAM, Suijkerbuijk KPM, Eriksson H, Hospers GAP, Mc Klop W, Acosta AT, Grijpink-Ongering L, Gonzalez M, van der Wal A, Al-Mamgani A, Spillane AJ, Scolyer RA, van de Wiel BA, van Akkooi ACJ, Long GV, Blank CU. European Journal of Cancer, (Nov 19 2024): 115141, doi:https://doi.org/10.1016/j.ejca.2024.115141.

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DNA Methylation Classes of Stage II and III Primary Melanomas and Their Clinical and Prognostic Significance.

2025-03-27T11:22:38+11:00November 8th, 2024|

Conway K, Edmiston SN, Vondras A, Reiner A, Corcoran DL, Shen R, Parrish EA, Hao H, Lin L, Kenney JM, Ilelaboye G, Kostrzewa CE, Kuan PF, Busam KJ, Lezcano C, Lee TK, Hernando E, Googe PB, Ollila DW, Moschos S, Gorlov I, Amos CI, Ernstoff MS, Cust AE, Wilmott JS, Scolyer RA, Mann GJ, Vergara IA, Ko J, Rees JR, Yan S, Nagore E, Bosenberg M, Rothberg BG, Osman I, Lee JE, Saenger Y, Bogner P, Thompson CL, Gerstenblith M, Holmen SL, Funchain P, Brunsgaard E, Depcik-Smith ND, Luo L, Boyce T, Orlow I, Begg CB, Berwick M, Thomas NE. JCO Precis Oncol, 8(Nov 2024): e2400375, doi:10.1200/po-24-00375.

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The Prognostic Significance of Tumoral Melanosis

2025-08-05T11:01:43+10:00October 2nd, 2024|

Potter Alison J, Ferguson Peter M, Lo Serigne N, Ahmed T, Rawson Robert V, Thompson John F, Long Georgina V, Scolyer Richard A. Journal of Cutaneous Pathology, (Oct 02 2024), doi:https://doi.org/10.1111/cup.14727.

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1090P High concurrent interferon gamma signature expression in the primary tumor and lymph node metastasis is associated with superior outcome upon neoadjuvant ipilimumab + nivolumab in stage III melanoma

2025-08-05T16:17:56+10:00September 27th, 2024|

Hoeijmakers L, Dimitriadis P, Cornelissen S, Reijers I, van de Wiel B, Scolyer RA, Saw RPM, Spillane AJ, Broeks A, Lopez-Yurda M, Grijpink-Ongering L, Hospers G, Menzies AM, van Akkooi ACJ, Van Houdt W, Long GV, Blank CU. Annals of Oncology, 35(Sep 24 2024): S721-S22, doi:10.1016/j.annonc.2024.08.1158.

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LBA41 Long-term survival with neoadjuvant therapy in melanoma: Updated pooled analysis from the International Neoadjuvant Melanoma Consortium (INMC)

2025-08-05T16:27:43+10:00September 24th, 2024|

Long GV, Blank CU, Amaria RN, Hieken TJ, Sandhu SK, Barros MJ, Mitchell TCC, Eroglu Z, Samoylenko IV, Rutkowski P, Johnson D, Pires da Silva I, Perry KA, Tawbi HA, Block MS, Ascierto PA, Burton E, van Akkooi ACJ, Scolyer RA, Menzies AM. Annals of Oncology, 35(Sep 24 2024): S1232, doi:10.1016/j.annonc.2024.08.2282.

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Predicting sentinel node positivity in patients with primary cutaneous melanoma: an international multicentre study validating and refining the MIA risk calculator

2025-08-05T16:44:22+10:00July 2nd, 2024|

Varey AH, Gjorup C, Hougaard Chakera A, Rosenkrantz Hölmich L, Moncrieff M, MacKenzie Ross A, Cassell O, Ma J, Brinch-Møller Weitemeyer M, Olofsson Bagge R, Klausen S, Calsavara VF, Duprat Neto JP, Bertolli E, Ch’ng S, Saw RP, Shannon KF, Spillane AJ, Nieweg OE, Stretch JR, Mann GJ, Geh JL, Martin RC, Sharon C, Karakousis GC, Kashani-Sabet M, Adigbli G, El-Sharouni MA, Haydu LE, Gershenwald JE, Scolyer RA, Thompson JF, Lo SN. EJC Skin Cancer, 2(Jul 02 2024), doi:10.1016/j.ejcskn.2024.100176.

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Neoadjuvant Nivolumab and Ipilimumab in Resectable Stage III Melanoma.

2025-07-31T10:36:06+10:00June 2nd, 2024|

Blank CU, Lucas MW, Scolyer RA, van de Wiel BA, Menzies AM, Lopez-Yurda M, Hoeijmakers LL, Saw RPM, Lijnsvelt JM, Maher NG, Pulleman SM, Gonzalez M, Torres Acosta A, van Houdt WJ, Lo SN, Kuijpers AMJ, Spillane A, Klop WMC, Pennington TE, Zuur CL, Shannon KF, Seinstra BA, Rawson RV, Haanen J, Ch’ng S, Naipal KAT, Stretch J, van Thienen JV, Rtshiladze MA, Wilgenhof S, Kapoor R, Meerveld-Eggink A, Grijpink-Ongering LG, van Akkooi ACJ, Reijers ILM, Gyorki DE, Grünhagen DJ, Speetjens FM, Vliek SB, Placzke J, Spain L, Stassen RC, Amini-Adle M, Lebbé C, Faries MB, Robert C, Ascierto PA, van Rijn R, van den Berkmortel F, Piersma D, van der Westhuizen A, Vreugdenhil G, Aarts MJB, Stevense-den Boer MAM, Atkinson V, Khattak M, Andrews MC, van den Eertwegh AJM, Boers-Sonderen MJ, Hospers GAP, Carlino MS, de Groot JB, Kapiteijn E, Suijkerbuijk KPM, Rutkowski P, Sandhu S, van der Veldt AAM, Long GV. N Engl J Med, (Jun 2 2024), doi:10.1056/NEJMoa2402604. TOP 1%

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Neoadjuvant Triplet Immune Checkpoint Blockade in Newly Diagnosed Glioblastoma.

2025-04-03T14:58:02+11:00April 28th, 2024|

Long G, Wilmott J, Shklovskaya E, Satgunseelan L, Mao Y, Perry K, Diefenbach R, Gide T, Shivalingam B, Buckland ME, Gonzalez M, Caixeiro NJ, Vergara I, Bai X, Hsiao E, Rawson R, da Silva I, Palendira U, Phan T, Menzies A, Carlino M, Quek C, Grimmond SM, Vissers J, Yeo D, Rasko JE, Khasraw M, Neytns B, Reardon D, Ashley DM, Wheeler H, Back M, Drummond J, Scolyer R, Rizos H. Nature Portfolio, (Preprint Apr 28 2024), doi:https://doi.org/10.21203/rs.3.rs-4255559/v1.

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The Impact of Next-generation Sequencing on Interobserver Agreement and Diagnostic Accuracy of Desmoplastic Melanocytic Neoplasms

2024-06-13T16:07:01+10:00April 9th, 2024|

Chen A, Sharma N, Patel P, Olivares S, Bahrami A, Barnhill RL, Blokx WAM, Bosenberg M, Busam KJ, de La Fouchardière A, Duncan LM, Elder DE, Ko JS, Landman G, Lazar AJ, Lezcano C, Lowe L, Maher N, Massi D, Messina J, Mihic-Probst D, Parker DC, Redpath M, Scolyer RA, Shea CR, Spatz A, Tron V, Xu X, Yeh I, Jung Yun S, Zembowicz A, Gerami P. Am J Surg Pathol, doi:10.1097/pas.0000000000002226.

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BRAF Mutated and Morphologically Spitzoid Tumors, a Subgroup of Melanocytic Neoplasms Difficult to Distinguish From True Spitz Neoplasms.

2025-04-03T12:00:03+11:00March 25th, 2024|

Gerami P, Chen A, Sharma N, Patel P, Hagstrom M, Kancherla P, Geraminejad T, Olivares S, Biswas A, Bosenberg M, Busam KJ, de La Fouchardière A, Duncan LM, Elder DE, Ko J, Landman G, Lazar AJ, Lowe L, Massi D, Mihic-Probst D, Parker DC, Scolyer RA, Shea CR, Zembowicz A, Yun SJ, Blokx WAM, Barnhill RL. Am J Surg Pathol, (Mar 25 2024), doi:10.1097/pas.0000000000002194. TOP 10%

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Pembrolizumab versus placebo as adjuvant therapy in resected stage IIB or IIC melanoma: Outcomes in histopathologic subgroups from the randomized, double-blind, phase 3 KEYNOTE-716 trial.

2024-05-09T12:13:11+10:00March 13th, 2024|

Schadendorf D, Luke JJ, Ascierto PA, Long GV, Rutkowski P, Khattak M, Del Vecchio M, de la Cruz Merino L, Mackiewicz J, Chiarion-Sileni V, Kirkwood JM, Robert C, Grob J-J, Dummer R, Carlino MS, Zhao Y, Fukunaga-Kalabis M, Krepler C, Eggermont AMM, Scolyer RA. Journal of Immunotherapy of Cancer.

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Health Economic Consequences Associated With COVID-19-Related Delay in Melanoma Diagnosis in Europe.

2025-04-03T15:16:08+11:00February 5th, 2024|

Maul LV, Jamiolkowski D, Lapides RA, Mueller AM, Hauschild A, Garbe C, Lorigan P, Gershenwald JE, Ascierto PA, Long GV, Wang-Evers M, Scolyer RA, Saravi B, Augustin M, Navarini AA, Legge S, Németh IB, Jánosi Á J, Mocellin S, Feller A, Manstein D, Zink A, Maul JT, Buja A, Adhikari K, Roider E. JAMA Netw Open, 7, no. 2, (Feb 5 2024): e2356479, doi:10.1001/jamanetworkopen.2023.56479. TOP 10%

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CD4+ T cell immunity against cutaneous melanoma encompasses multifaceted MHC II-dependent responses.

2025-05-08T09:49:11+10:00January 19th, 2024|

Bawden EG, Wagner T, Schröder J, Effern M, Hinze D, Newland L, Attrill GH, Lee AR, Engel S, Freestone D, de Lima Moreira M, Gressier E, McBain N, Bachem A, Haque A, Dong R, Ferguson AL, Edwards JJ, Ferguson PM, Scolyer RA, Wilmott JS, Jewell CM, Brooks AG, Gyorki DE, Palendira U, Bedoui S, Waithman J, Hochheiser K, Hölzel M, Gebhardt T. Sci Immunol, 9, no. 91, (Jan 19 2024): eadi9517, doi:10.1126/sciimmunol.adi9517. TOP 10%

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Pembrolizumab versus placebo as adjuvant therapy in resected stage IIB or IIC melanoma: Outcomes in histopathologic subgroups from the randomized, double-blind, phase 3 KEYNOTE-716 trial.

2025-05-08T12:44:24+10:00December 9th, 2023|

Schadendorf D, Luke JJ, Ascierto PA, Long GV, Rutkowski P, Khattak M, Del Vecchio M, de la Cruz Merino L, Mackiewicz J, Chiarion-Sileni V, Kirkwood JM, Robert C, Grob J-J, Dummer R, Carlino MS, Zhao Y, Fukunaga-Kalabis M, Krepler C, Eggermont AMM, Scolyer RA. Journal of Immunotherapy of Cancer, (accepted Dec 09 2023).

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Role of Concurrent Ultrasound Surveillance of Sentinel Node-Positive Node Fields in Melanoma Patients Having Routine Cross-Sectional Imaging.

2025-05-08T10:12:00+10:00November 15th, 2023|

Gjorup CA, Woodford R, Li I, Carlino MS, Ch’ng S, Chung D, Hsiao E, Lo SN, London K, Long GV, Menzies AM, Nieweg OE, Pennington TE, Rtshiladze MA, Saw RPM, Scolyer RA, Shannon KF, Spillane AJ, Stretch JR, Thompson JF, Varey AHR, van Akkooi ACJ. Ann Surg Oncol, (Nov 15 2023), doi:10.1245/s10434-023-14526-9.

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Comparison of humans versus mobile phone-powered artificial intelligence for the diagnosis and management of pigmented skin cancer in secondary care: a multicentre, prospective, diagnostic, clinical trial

2025-09-10T16:30:06+10:00October 1st, 2023|

Menzies SW, Sinz C, Menzies M, Lo SN, Yolland W, Lingohr J, Razmara M, Tschandl P, Guitera P, Scolyer RA, Boltz F, Borik-Heil L, Herbert Chan H, Chromy D, Coker DJ, Collgros H, Eghtedari M, Corral Forteza M, Forward E, Gallo B, Geisler S, Gibson M, Hampel A, Ho G, Junez L, Kienzl P, Martin A, Moloney FJ, Regio Pereira A, Ressler JM, Richter S, Silic K, Silly T, Skoll M, Tittes J, Weber P, Weninger W, Weiss D, Woo-Sampson P, Zilberg C, Kittler H. The Lancet Digital Health, 5, no. 10: e679-e91, doi:10.1016/S2589-7500(23)00130-9. TOP 1%

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Looking beyond workforce parity: addressing gender inequity in pathology

2025-09-10T14:29:33+10:00July 25th, 2023|

McKenzie CA, Gupta R, Jackett L, Anderson L, Chen V, Dahlstrom JE, Dray M, Farshid G, Hemmings C, Karim R, Kench JG, Klebe S, Kramer N, Kumarasinghe P, Maclean F, Morey A, Nguyen MA, O’Toole S, Rowbotham B, Salisbury ELC, Scolyer RA, Stewart K, Waring L, Cooper CL, Cooper WA. Pathology, doi:https://doi.org/10.1016/j.pathol.2023.07.002.

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Looking beyond workforce parity: addressing gender inequity in pathology.

2025-04-24T14:19:46+10:00July 25th, 2023|

McKenzie CA, Gupta R, Jackett L, Anderson L, Chen V, Dahlstrom JE, Dray M, Farshid G, Hemmings C, Karim R, Kench JG, Klebe S, Kramer N, Kumarasinghe P, Maclean F, Morey A, Nguyen MA, O’Toole S, Rowbotham B, Salisbury ELC, Scolyer RA, Stewart K, Waring L, Cooper CL, Cooper WA. Pathology, (Jul 25 2023), doi:https://doi.org/10.1016/j.pathol.2023.07.002.

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Cutaneous melanoma: a contemporary overview.

2025-05-01T09:29:57+10:00July 24th, 2023|

Georgina V Long, Susan M Swetter, Alexander M Menzies, Jeffrey E Gershenwald, Richard A Scolyer. Lancet 2023 Jul 24;S0140-6736(23)00821-8. doi: 10.1016/S0140-6736(23)00821-8.

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Neoadjuvant immunotherapy for melanoma is now ready for clinical practice.

2025-04-24T13:43:51+10:00May 16th, 2023|

Garbe C, Dummer R, Amaral T, Amaria RN, Ascierto PA, Burton EM, Dreno B, Eggermont AMM, Hauschild A, Hoeller C, Kaufmann R, Lebbe C, Mandala M, Menzies AM, Moreno D, Michielin O, Nathan P, Patel SP, Robert C, Schadendorf D, Lorigan PC, Scolyer RA, Tawbi HA, van de Wiel BA, Blank C, Long GV. Nature Medicine, (May 16 2023), doi:10.1038/s41591-023-02336-1. TOP 1%

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Regarding: Predicting Regional Lymph Node Recurrence in The Modern Age of Tumor-Positive Sentinel Node Melanoma.

2025-04-24T14:54:48+10:00May 6th, 2023|

Thompson JF, Hyngstrom J, Caracò C, Zager JS, Jahkola T, Bowles TL, Pennacchioli E, Hoekstra HJ, Moncrieff M, Ingvar C, van Akkooi A, Sabel MS, Levine EA, Henderson M, Dummer R, Rossi CR, Kane JM, Trocha S, Wright F, Byrd DR, Matter M, MacKenzie-Ross A, Kelley MC, Terheyden P, Huston TL, Wayne JD, Neuman H, Smithers BM, Desai D, Gershenwald JE, Schneebaum S, Gesierich A, Jacobs LK, Lewis JM, O’Donoghue C, Sardi A, McKinnon JG, Slingluff CL, Farma JM, Schultz E, Scheri RP, Vidal-Sicart S, Testori AAE, Scolyer RA, Elashoff DE, Cochran AJ, Faries MB. Annals of Surgical Oncology, (May 06 2023), doi:10.1245/s10434-023-13570-9.

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REPLY to MS#JAAD-D-23-00002R1.

2023-05-15T20:05:54+10:00March 17th, 2023|

El Sharouni MA, Lo SN, Scolyer RA, van Gils CH, Thompson JF. J Am Acad Dermatol. 2023 Mar 17:S0190-9622(23)00440-1. doi: 10.1016/j.jaad.2023.03.008. Epub ahead of print. PMID: 36935017.

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IFN-γ signature enables selection of neoadjuvant treatment in patients with stage III melanoma.

2023-05-14T19:44:01+10:00March 15th, 2023|

Reijers ILM, Rao D, Versluis JM, Menzies AM, Dimitriadis P, Wouters MW, Spillane AJ, Klop WMC, Broeks A, Bosch LJW, Lopez-Yurda M, van Houdt WJ, Rawson RV, Grijpink-Ongering LG, Gonzalez M, Cornelissen S, Bouwman J, Sanders J, Plasmeijer E, Elshot YS, Scolyer RA, van de Wiel BA, Peeper DS, van Akkooi ACJ, Long GV, Blank CU. J Exp Med. 2023 May 1;220(5):e20221952. doi: 10.1084/jem.20221952. Epub 2023 Mar 15. PMID: 36920329; PMCID: PMC10037109.

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Nicotinamide for Skin-Cancer Chemoprevention in Transplant Recipients.

2023-05-14T17:39:43+10:00March 2nd, 2023|

Allen NC, Martin AJ, Snaidr VA, Eggins R, Chong AH, Fernandéz-Peñas P, Gin D, Sidhu S, Paddon VL, Banney LA, Lim A, Upjohn E, Schaider H, Ganhewa AD, Nguyen J, McKenzie CA, Prakash S, McLean C, Lochhead A, Ibbetson J, Dettrick A, Landgren A, Allnutt KJ, Allison C, Davenport RB, Mumford BP, Wong B, Stagg B, Tedman A, Gribbin H, Edwards HA, De Rosa N, Stewart T, Doolan BJ, Kok Y, Simpson K, Low ZM, Kovitwanichkanont T, Scolyer RA, Dhillon HM, Vardy JL, Chadban SJ, Bowen DG, Chen AC, Damian DL. N Engl J Med. 2023 Mar 2;388(9):804-812. doi: 10.1056/NEJMoa2203086. PMID: 36856616.

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Intratumoral CD16+ macrophages are associated with clinical outcomes of patients with metastatic melanoma treated with combination anti-PD-1 and anti-CTLA-4 therapy.

2023-05-15T20:22:46+10:00February 15th, 2023|

Lee H, Ferguson AL, Quek C, Vergara IA, Pires daSilva I, Allen R, Gide TN, Conway JW, Koufariotis LT, Hayward NK, Waddell N, Carlino MS, Menzies AM, Saw RPM, Shklovskaya E, Rizos H, Lo S, Scolyer RA, Long GV, Palendira U, Wilmott JS. Clin Cancer Res. 2023 Feb 15:CCR-22-2657. doi: 10.1158/1078-0432.CCR-22-2657. Epub ahead of print. PMID: 36790412.

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Clinical Features Associated with Outcomes and Biomarker Analysis of Dabrafenib plus Trametinib Treatment in Patients with BRAF-Mutant Melanoma Brain Metastases.

2023-05-14T16:54:39+10:00February 1st, 2023|

Wilmott JS, Tawbi H, Engh JA, Amankulor NM, Shivalingam B, Banerjee H, Vergara IA, Lee H, Johansson PA, Ferguson PM, Saiag P, Robert C, Grob JJ, Butterfield LH, Scolyer RA, Kirkwood JM, Long GV, Davies MA. Clin Cancer Res, 29, no. 3, (Feb 1 2023): 521-31, doi:10.1158/1078-0432.Ccr-22-2581

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IFNγ signaling sensitizes melanoma cells to BH3 Mimetics.

2023-05-14T16:40:18+10:00February 1st, 2023|

Ming Z, Lim SY, Stewart A, Pedersen B, Shklovskaya E, Menzies AM, Carlino MS, Kefford RF, Lee JH, Scolyer RA, Long GV, Rizos H.  Journal of Investigative Dermatology, (Feb 01 2023), doi:https://doi.org/10.1016/j.jid.2023.01.017.

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Survival update of neoadjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma in the OpACIN and OpACIN-neo trials.

2023-05-14T16:01:42+10:00January 18th, 2023|

Versluis JM, Menzies AM, Sikorska K, Rozeman EA, Saw RPM, van Houdt WJ, Eriksson H, Klop WMC, Ch’ng S, van Thienen JV, Mallo H, Gonzalez M, Torres Acosta A, Grijpink-Ongering LG, van der Wal A, Bruining A, van de Wiel BA, Scolyer RA, Haanen J, Schumacher TN, van Akkooi ACJ, Long GV, Blank CU.  Ann Oncol, (Jan 18 2023), doi:10.1016/j.annonc.2023.01.004

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Revision of the Melanocytic Pathology Assessment Tool and Hierarchy for Diagnosis Classification Schema for Melanocytic Lesions: A Consensus Statement

2023-04-03T10:14:47+10:00January 3rd, 2023|

Barnhill RL, Elder DE, Piepkorn MW, Knezevich SR, Reisch LM, Eguchi MM, Bastian BC, Blokx W, Bosenberg M, Busam KJ, Carr R, Cochran A, Cook MG, Duncan LM, Elenitsas R, de la Fouchardière A, Gerami P, Johansson I, Ko J, Landman G, Lazar AJ, Lowe L, Massi D, Messina J, Mihic-Probst D, Parker DC, Schmidt B, Shea CR, Scolyer RA, Tetzlaff M, Xu X, Yeh I, Zembowicz A, Elmore JG.  JAMA Netw Open. 2023 Jan 3;6(1):e2250613. doi: 10.1001/jamanetworkopen.2022.50613. PMID: 36630138.

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Clinical features associated with outcomes and biomarker analysis of dabrafenib plus trametinib treatment in patients with BRAF-mutant melanoma brain metastases.

2023-01-21T22:57:07+11:00December 7th, 2022|

Wilmott JS, Tawbi H, Engh JA, Amankulor NM, Shivalingam B, Banerjee H, Vergara IA, Lee H, Johansson PA, Ferguson PM, Saiag P, Robert C, Grob JJ, Butterfield LH, Scolyer RA, Kirkwood JM, Long GV, Davies MA. Clin Cancer Res. 2022 Dec 7:CCR-22-2581. doi: 10.1158/1078-0432.CCR-22-2581. Epub ahead of print. PMID: 36477181.

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Obesity is associated with altered tumor metabolism in metastatic melanoma.

2022-11-19T22:24:52+11:00September 27th, 2022|

Hahn AW, Menk AV, Rivadeneira DB, Augustin RC, Xu M, Li J, Wu X, Mishra AK, Gide TN, Quek C, Zang Y, Spencer CN, Menzies AM, Daniel CR, Hudgens CW, Nowicki T, Haydu LE, Khan MAW, Gopalakrishnan V, Burton EM, Malke J, Simon JM, Bernatchez C, Putluri N, Woodman SE, Gopal Y N V, Guerrieri R, Fischer GM, Wang J, Wani KM, Thompson JF, Lee JE, Hwu P, Ajami N, Gershenwald JE, Long GV, Scolyer RA, Tetzlaff MT, Lazar AJ, Schadendorf D, Wargo JA, Kirkwood JM, DeBerardinis RJ, Liang H, Futreal A, Zhang J, Wilmott JS, Peng W, Davies MA, Delgoffe GM, Najjar YG, McQuade JL. Clin Cancer Res. 2022 Sep 27:CCR-22-2661. doi: 10.1158/1078-0432.CCR-22-2661. Epub ahead of print. PMID: 36166093.

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Hypoxia controls the glycome signature and galectin-8 – ligand axis to promote pro-tumorigenic properties of metastatic melanoma.

2022-11-19T22:31:02+11:00September 26th, 2022|

Chakraborty A, Perez M, Carroll JD, Antonopoulos A, Dell A, Ortega L, Mohammed NBB, Wells M, Staudinger C, Griswold A, Chandler KB, Marrero C, Jimenez R, Tani Y, Wilmott JS, Thompson JF, Wang W, Sackstein R, Scolyer RA, Murphy GF, Haslam SM, Dimitroff CJ. J Invest Dermatol. 2022 Sep 26:S0022-202X(22)01931-5. doi: 10.1016/j.jid.2022.07.033. Epub ahead of print. PMID: 36174713.

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Comparative genomics provides etiological and biological insights into melanoma subtypes

2022-10-09T21:35:02+11:00September 13th, 2022|

Newell F, Johansson PA, Wilmott JS, Nones K, Lakis V, Pritchard AL, Lo SN, Rawson RV, Kazakoff SH, Colebatch AJ, Koufariotis LT, Ferguson PM, Wood S, Leonard C, Law MH, Brooks KM, Broit N, Palmer JM, Couts KL, Vergara IA, Long GV, Barbour AP, Nieweg OE, Shivalingam B, Robinson WA, Stretch JR, Spillane AJ, Saw RPM, Shannon KF, Thompson JF, Mann GJ, Pearson JV, Scolyer RA, Waddell N, Hayward NK. Cancer Discov. 2022 Sep 13:CD-22-0603. doi: 10.1158/2159-8290.CD-22-0603. Epub ahead of print. PMID: 36098958.

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Diet-driven microbial ecology underpins associations between cancer immunotherapy outcomes and the gut microbiome.

2022-10-23T19:53:17+11:00September 1st, 2022|

Simpson RC, Shanahan ER, Batten M, Reijers ILM, Read M, Silva IP, Versluis JM, Ribero R, Angelatos AS, Tan J, Adhikari C, Menzies AM, Saw RPM, Gonzalez M, Shannon KF, Spillane AJ, Velickovic R, Lazar AJ, Damania AV, Mishra AK, Chelvanambi M, Banerjee A, Ajami NJ, Wargo JA, Macia L, Holmes AJ, Wilmott JS, Blank CU, Scolyer RA, Long GV. Nat Med 2022 Sep 22. doi: 10.1038/s41591-022-01965-2. Epub ahead of print.

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Therapeutic Value of Sentinel Lymph Node Biopsy in Patients With Melanoma: A Randomized Clinical Trial.

2025-05-01T10:00:58+10:00August 3rd, 2022|

Crystal JS, Thompson JF, Hyngstrom J, Caraco C, Zager JS, Jahkola T, Bowles TL, Pennacchioli E, Beitsch PD, Hoekstra HJ, Moncrieff M, Ingvar C, van Akkooi A, Sabel MS, Levine EA, Agnese D, Henderson M, Dummer R, Neves RI, Rossi CR, Kane JM, Trocha SD, Wright F, Byrd DR, Dillon LD, Matter M, Hsueh EC, MacKenzie-Ross A, Kelley M, Terheyden P, Huston TL, Wayne JD, Neuman HB, Smithers BM, Ariyan CE, Desai DC, Gershenwald JE, Schneebaum S, Gesierich A, Jacobs LK, Lewis JM, McMasters KM, O’Donoghue C, van der Westhuizen A, Sardi A, Barth R, Barone R, McKinnon JG, Slingluff CL, Farma JM, Schultz E, Scheri RP, Vidal-Sicart S, Molina M, Testori AAE, Foshag LJ, van Kreuningan L, Wang H-J, Sim M-S, Scolyer R, Elashoff DE, Cochran AJ, Faries MD. JAMA Surgery, (Aug 03 2022), doi:10.1001/jamasurg.2022.2055.

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Pembrolizumab versus placebo as adjuvant therapy in completely resected stage IIB or IIC melanoma (KEYNOTE-716): a randomised, double-blind, phase 3 trial

2025-10-30T15:22:13+11:00August 1st, 2022|

Luke JJ, Rutkowski P, Queirolo P, Del Vecchio M, Mackiewicz J, Chiarion-Sileni V, de la Cruz Merino L, Khattak MA, Schadendorf D, Long GV, Ascierto PA, Mandala M, De Galitiis F, Haydon A, Dummer R, Grob J-J, Robert C, Carlino MS, Mohr P, Poklepovic A, Sondak VK, Scolyer RA, Kirkwood JM, Chen K, Diede SJ, Ahsan S, Ibrahim N, Eggermont AMM. The Lancet, (Mar 31 2022), doi:10.1016/S0140-6736(22)00562-1. TOP 1%

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Landscape of mutations in early stage primary cutaneous melanoma: An InterMEL study.

2025-05-01T10:24:18+10:00July 25th, 2022|

Luo L, Shen R, Arora A, Orlow I, Busam KJ, Lezcano C, Lee TK, Hernando E, Gorlov I, Amos C, Ernstoff MS, Seshan VE, Cust AE, Wilmott J, Scolyer Richard A, Mann G, Nagore E, Funchain P, Ko J, Ngo P, Edmiston SN, Conway K, Googe PB, Ollila D, Lee JE, Fang S, Rees JR, Thompson CL, Gerstenblith M, Bosenberg M, Gould Rothberg B, Osman I, Saenger Y, Reynolds AZ, Schwartz M, Boyce T, Holmen S, Brunsgaard E, Bogner P, Kuan PF, Wiggins C, Thomas Nancy E, Begg CB, Berwick M, InterMEL. Pigment Cell & Melanoma Research, (Jul 25 2022), doi:https://doi.org/10.1111/pcmr.13058.

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Clinical Outcomes and Risk Stratification of Early-Stage Melanoma Micrometastases From an International Multicenter Study: Implications for the Management of American Joint Committee on Cancer IIIA Disease.

2025-05-01T11:52:20+10:00July 18th, 2022|

Moncrieff MD, Lo SN, Scolyer RA, Heaton MJ, Nobes JP, Snelling AP, Carr MJ, Nessim C, Wade R, Peach AH, Kisyova R, Mason J, Wilson ED, Nolan G, Jones RP, Johansson I, Bagge RO, Wright LJ, Patel NG, Sondak VK, Thompson JF, Zager JS. Journal of Clinical Oncology, (Jul 18 2022): JCO.21.02488, doi:10.1200/jco.21.02488.

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Representativeness of the Index Lymph Node for Total Nodal Basin in Pathologic Response Assessment After Neoadjuvant Checkpoint Inhibitor Therapy in Patients With Stage III Melanoma

2025-08-20T16:51:49+10:00April 1st, 2022|

Irene L M ReijersRobert V RawsonAndrew J ColebatchElisa A RozemanAlex M MenziesAlexander C J van AkkooiKerwin F ShannonMichel W WoutersRobyn P M SawWinan J van HoudtCharlotte L ZuurOmgo E NiewegSydney Ch’ngW Martin C KlopAndrew J SpillaneGeorgina V LongRichard A ScolyerBart A van de WielChristian U Blank. JAMA Surg. 157(4):335–342. doi:10.1001/jamasurg.2021.7554

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Anatomic position determines oncogenic specificity in melanoma.

2025-07-24T12:09:45+10:00March 30th, 2022|

Weiss JM, Hunter MV, Cruz NM, Baggiolini A, Tagore M, Ma Y, Misale S, Marasco M, Simon-Vermot T, Campbell NR, Newell F, Wilmott JS, Johannson PA, Thompson JF, Long GV, Pearson JV, Mann GJ, Scolyer RA, Waddell N, Montal ED, Huang T-H, Jonnson P, Donoghue MTA, Harris CC, Taylor BS, Xu T, Chaligne R, Shliaha PV, Hendrickson R, Jungbluth AA, Lezcano C, Koche R, Studer L, Ariyan CE, Solit DB, Wolchok JD, Merghoub T, Rosen N, Hayward NK, White RM. Nature, (March 30 2022).

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Anatomic position determines oncogenic specificity in melanoma

2025-11-10T14:23:23+11:00March 22nd, 2022|

Weiss JM, Hunter MV, Cruz NM, Baggiolini A, Tagore M, Ma Y, Misale S, Marasco M, Simon-Vermot T, Campbell NR, Newell F, Wilmott JS, Johansson PA, Thompson JF, Long GV, Pearson JV, Mann GJ, Scolyer RA, Waddell N, Montal ED, Huang T-H, Jonsson P, Donoghue MTA, Harris CC, Taylor BS, Xu T, Chaligné R, Shliaha PV, Hendrickson R, Jungbluth AA, Lezcano C, Koche R, Studer L, Ariyan CE, Solit DB, Wolchok JD, Merghoub T, Rosen N, Hayward NK, White RM. Nature, 604, no. 7905, (Apr 01 2022): 354-61, doi:10.1038/s41586-022-04584-6. TOP 1%

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Clinical Models to Define Response and Survival With Anti–PD-1 Antibodies Alone or Combined With Ipilimumab in Metastatic Melanoma

2025-11-05T16:13:27+11:00February 10th, 2022|

Silva IPd, Ahmed T, McQuade JL, Nebhan CA, Park JJ, Versluis JM, Serra-Bellver P, Khan Y, Slattery T, Oberoi HK, Ugurel S, Haydu LE, Herbst R, Utikal J, Pföhler C, Terheyden P, Weichenthal M, Gutzmer R, Mohr P, Rai R, Smith JL, Scolyer RA, Arance AM, Pickering L, Larkin J, Lorigan P, Blank CU, Schadendorf D, Davies MA, Carlino MS, Johnson DB, Long GV, Lo SN, Menzies AM. Journal of Clinical Oncology, 0, no. 0, (Feb 10 2022): JCO.21.01701, doi:10.1200/jco.21.01701. TOP 10%

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Clinical Models to Define Response and Survival With Anti-PD-1 Antibodies Alone or Combined With Ipilimumab in Metastatic Melanoma.

2025-07-24T11:52:41+10:00February 10th, 2022|

Pires da Silva I, Ahmed T, McQuade JL, Nebhan C, Park JJ, Versluis J, Serra-Bellver P, Khan Y, Slattery T, Oberoi H, Ugurel S, Haydu LE, Herbst R, Utikal J, Pfoehler C, Terheyden P, Weichenthal M, Gutzmer R, Mohr P, Rai R, Smith JL, Scolyer RA, Arance A, Pickering L, Larkin J, Lorigan P, Blank CU, Schadendorf D, Davies MA, Carlino MS, Johnson DB, Long GV, Lo SN, Menzies AM. Journal of Clinical Oncology, (Jan 23 (accepted) 2022).

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Representativeness of the Index Lymph Node for Total Nodal Basin in Pathologic Response Assessment After Neoadjuvant Checkpoint Inhibitor Therapy in Patients With Stage III Melanoma

2025-11-05T15:50:38+11:00February 9th, 2022|

Reijers ILM, Rawson RV, Colebatch AJ, Rozeman EA, Menzies AM, van Akkooi ACJ, Shannon KF, Wouters MW, Saw RPM, van Houdt WJ, Zuur CL, Nieweg OE, Ch’ng S, Klop WMC, Spillane AJ, Long GV, Scolyer RA, van de Wiel BA, Blank CU. JAMA Surgery, (Feb 9 2022), doi:10.1001/jamasurg.2021.7554. TOP 1%

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Neoadjuvant Systemic Therapy (NAST) in Patients with Melanoma: Surgical Considerations by the International Neoadjuvant Melanoma Consortium (INMC)

2025-11-10T14:02:39+11:00January 28th, 2022|

van Akkooi ACJ, Hieken TJ, Burton EM, Ariyan C, Ascierto PA, Asero SVMA, Blank CU, Block MS, Boland GM, Caraco C, Chng S, Davidson BS, Duprat Neto JP, Faries MB, Gershenwald JE, Grunhagen DJ, Gyorki DE, Han D, Hayes AJ, van Houdt WJ, Karakousis GC, Klop WMC, Long GV, Lowe MC, Menzies AM, Olofsson Bagge R, Pennington TE, Rutkowski P, Saw RPM, Scolyer RA, Shannon KF, Sondak VK, Tawbi H, Testori AAE, Tetzlaff MT, Thompson JF, Zager JS, Zuur CL, Wargo JA, Spillane AJ, Ross MI, International Neoadjuvant Melanoma C. Annals of Surgical Oncology, (Jan 28 2022), doi:10.1245/s10434-021-11236-y. TOP 10%

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Neoadjuvant Systemic Therapy (NAST) in Patients with Melanoma: Surgical Considerations by the International Neoadjuvant Melanoma Consortium (INMC).

2025-07-24T12:06:17+10:00January 28th, 2022|

van Akkooi ACJ, Kieken TJ, Burton eM, Ariyan c, Ascierto P, Asero s, Blank C, Block MS, Boland G, Caraco C, Davidson S, Duprat J, Faries M, Gershenwald J, Grunhagen D, Gyorki dE, Han D, Hayes A, van Houdt WJ, Karakousis g, Klop M, Long G, Lowe MC, Menzies A, Olofsson R, Ross MI, Rutkowski P, Saw RPM, Scolyer r, Sondak v, Spillane AJ, Tawbi H, Testori AAE, Thompson J, Zager J, Zuur CL, Wargo JA. Annals of Surgical Oncology., (Jan 28 2022).

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Pathology: the next chapter

2025-11-05T16:01:44+11:00January 10th, 2022|

Scolyer RA. Pathology, 54, no. 1, (Feb 2022): 4-5, doi:10.1016/j.pathol.2021.12.001.

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Multiomic profiling of checkpoint inhibitor-treated melanoma: Identifying predictors of response and resistance, and markers of biological discordance

2025-11-05T15:16:06+11:00January 10th, 2022|

Newell F, Pires da Silva I, Johansson PA, Menzies AM, Wilmott JS, Addala V, Carlino MS, Rizos H, Nones K, Edwards JJ, Lakis V, Kazakoff SH, Mukhopadhyay P, Ferguson PM, Leonard C, Koufariotis LT, Wood S, Blank CU, Thompson JF, Spillane AJ, Saw RPM, Shannon KF, Pearson JV, Mann GJ, Hayward NK, Scolyer RA, Waddell N, Long GV. Cancer Cell, 40, no. 1, (Jan 10 2022): 88-102.e7, doi:10.1016/j.ccell.2021.11.012. TOP 10%

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Assessing the Potential for Patient-led Surveillance After Treatment of Localized Melanoma (MEL-SELF): A Pilot Randomized Clinical Trial

2025-10-20T16:13:28+11:00January 1st, 2022|

Ackermann DM, Dieng M, Medcalf E, Jenkins MC, van Kemenade CH, Janda M, Turner RM, Cust AE, Morton RL, Irwig L, Guitera P, Soyer HP, Mar V, Hersch JK, Low D, Low C, Saw RPM, Scolyer RA, Drabarek D, Espinoza D, Azzi A, Lilleyman AM, Smit AK, Murchie P, Thompson JF, Bell KJL. JAMA Dermatol, 158, no. 1, (Jan 1 2022): 33-42, doi:10.1001/jamadermatol.2021.4704. TOP 1%

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BRAF mutation testing for patients diagnosed with stage III or stage IV melanoma: practical guidance for the Australian setting

2025-11-05T16:05:34+11:00December 21st, 2021|

Scolyer RA, Atkinson V, Gyorki DE, Lambie D, O’Toole S, Saw RPM, Amanuel B, Angel CM, Button-Sloan AE, Carlino MS, Ch’ng S, Colebatch AJ, Daneshvar D, Pires da Silva I, Dawson T, Ferguson PM, Foster-Smith E, Fox SB, Gill AJ, Gupta R, Henderson MA, Hong AM, Howle JR, Jackett LA, James C, Lee CS, Lochhead A, Loh D, McArthur GA, McLean CA, Menzies AM, Nieweg OE, O’Brien BH, Pennington TE, Potter AJ, Prakash S, Rawson RV, Read RL, Rtshiladze MA, Shannon KF, Smithers BM, Spillane AJ, Stretch JR, Thompson JF, Tucker P, Varey AHR, Vilain RE, Wood BA, Long GV. Pathology, 54, no. 1, (Feb 2022): 6-19, doi:10.1016/j.pathol.2021.11.002.

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Multiomic profiling of checkpoint inhibitor-treated melanoma: Identifying predictors of response and resistance, and markers of biological discordance.

2025-07-24T13:09:58+10:00December 21st, 2021|

Newell F, Pires da Silva I, Johansson PA, Menzies AM, Wilmott JS, Addala V, Carlino MS, Rizos H, Nones K, Edwards JJ, Lakis V, Kazakoff SH, Mukhopadhyay P, Ferguson PM, Leonard C, Koufariotis LT, Wood S, Blank CU, Thompson JF, Spillane AJ, Saw RPM, Shannon KF, Pearson JV, Mann GJ, Hayward NK, Scolyer RA, Waddell N, Long GV. Cancer Cell, (Dec 21 2021), doi:10.1016/j.ccell.2021.11.012.

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BRAF mutation testing for patients diagnosed with stage III or stage IV melanoma: practical guidance for the Australian setting.

2025-07-24T13:23:31+10:00December 19th, 2021|

Scolyer RA, Atkinson V, Gyorki DE, Lambie D, O’Toole S, Saw RPM, Amanuel B, Angel CM, Button-Sloan AE, Carlino MS, Ch’ng S, Colebatch AJ, Daneshvar D, Pires da Silva I, Dawson T, Ferguson PM, Foster-Smith E, Fox SB, Gill AJ, Gupta R, Henderson MA, Hong AM, Howle JR, Jackett LA, James C, Lee CS, Lochhead A, Loh D, McArthur GA, McLean CA, Menzies AM, Nieweg OE, O’Brien BH, Pennington TE, Potter AJ, Prakash S, Rawson RV, Read RL, Rtshiladze MA, Shannon KF, Smithers BM, Spillane AJ, Stretch JR, Thompson JF, Tucker P, Varey AHR, Vilain RE, Wood BA, Long GV. Pathology, (Dec 19 2021), doi:10.1016/j.pathol.2021.11.002.

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Impact of Next-generation Sequencing on Interobserver Agreement and Diagnosis of Spitzoid Neoplasms.

2022-07-23T17:39:25+10:00December 1st, 2021|

Benton S, Zhao J, Zhang B, Bahrami A, Barnhill RL, Busam K, Cerroni L, Cook MG, de la Fouchardière A, Elder DE, Johansson I, Landman G, Lazar A, LeBoit P, Lowe L, Massi D, Duncan LM, Messina J, Mihic-Probst D, Mihm MC Jr, Piepkorn MW, Schmidt B, Scolyer RA, Shea CR, Tetzlaff MT, Tron VA, Xu X, Yeh I, Yun SJ, Zembowicz A, Gerami P. Am J Surg Pathol. 2021 Dec 1;45(12):1597-1605

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Assessing the Potential for Patient-led Surveillance After Treatment of Localized Melanoma (MEL-SELF): A Pilot Randomized Clinical Trial.

2022-07-23T17:22:11+10:00November 24th, 2021|

Ackermann DM, Dieng M, Medcalf E, Jenkins MC, van Kemenade CH, Janda M, Turner RM, Cust AE, Morton RL, Irwig L, Guitera P, Soyer HP, Mar V, Hersch JK, Low D, Low C, Saw RPM, Scolyer RA, Drabarek D, Espinoza D, Azzi A, Lilleyman AM, Smit AK, Murchie P, Thompson JF, Bell KJL. JAMA Dermatol. (Epub 24 Nov 2021)

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Combined presentation and immunogenicity analysis reveals a recurrent RAS.Q61K neoantigen in melanoma.

2022-07-23T20:29:32+10:00October 15th, 2021|

Peri A, Greenstein E, Alon M, Pai JA, Dingjan T, Reich-Zeliger S, Barnea E, Barbolin C, Levy R, Arnedo-Pac C, Kalaora S, Dassa B, Feldmesser E, Shang P, Greenberg P, Levin Y, Benedek G, Levesque MP, Adams DJ, Lotem M, Wilmott JS, Scolyer RA, Jönsson GB, Admon A, Rosenberg SA, Cohen CJ, Niv MY, Lopez-Bigas N, Satpathy AT, Friedman N, Samuels Y. J Clin Invest. 2021 Oct 15;131(20):e129466.

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Can patient-led surveillance detect subsequent new primary or recurrent melanomas and reduce the need for routinely scheduled follow-up? A protocol for the MEL-SELF randomised controlled trial.

2025-07-24T14:07:46+10:00May 21st, 2021|

Deonna Ackermann*, Amelia K Smit*, Monika Janda, Cathelijne van Kemenade, Mbathio Dieng, Rachael L Morton, Robin Turner, Anne E Cust, Les Irwig, Jolyn Hersch, Pascale Guitera, H. Peter Soyer, Victoria Mar, Robyn P M Saw, Donald Low, Cynthia Low, Dorothy Drabarek, David Espinoza, Jon Emery, Peter Murchie, John Thompson, Richard A. Scolyer, Anthony Azzi, Alister Lilleyman, Katy Bell (X contributed equally to this paper) (*contributed equally to this paper). 3.21: accepted for publication in Trials.

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The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics.

2025-05-29T12:22:13+10:00May 4th, 2021|

Giblin W, Bringman-Rodenbarger L, Guo AH, Kumar S, Monovich AC, Mostafa AM, Skinner ME, Azar M, Mady AS, Chung CH, Kadambi N, Melong KA, Lee HJ, Zhang L, Sajjakulnukit P, Trefely S, Varner EL, Iyer S, Wang M, Wilmott JS, Soyer HP, Sturm RA, Pritchard AL, Andea AA, Scolyer RA, Stark MS, Scott DA, Fullen DR, Bosenberg MW, Chandrasekaran S, Nikolovska-Coleska Z, Verhaegen ME, Snyder NW, Rivera MN, Osterman A, Lyssiotis CA, Lombard DB. J Clin Invest. (Epub 4 May 2021)

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Pembrolizumab versus placebo as adjuvant therapy in completely resected stage IIB or IIC melanoma (KEYNOTE-716): a randomised, double-blind, phase 3 trial

2022-07-25T21:12:03+10:00April 30th, 2021|

Jason J Luke, Prof Piotr Rutkowski, Paola Queirolo, Michele Del Vecchio, Prof Jacek Mackiewicz, Vanna Chiarion-Sileni, Luis de la Cruz Merino, Prof Muhammad A Khattak, Prof Dirk Schadendorf, Prof Georgina V Long, Paolo A Ascierto, Mario Mandala, Federica De Galitiis, Andrew Haydon, Reinhard Dummer, Prof Jean-Jacques Grob, Caroline Robert, Matteo S Carlino, Peter Mohr, Andrew Poklepovic, Prof Vernon K Sondak, Prof Richard A Scolyer, John M Kirkwood, Ke Chen, Scott J Diede, Sama Ahsan, Nageatte Ibrahim, Prof Alexander M M. Lancet. (30 Apr 2022)

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Pathological response and tumour bed histopathological features correlate with survival following neoadjuvant immunotherapy in stage III melanoma.

2025-05-29T15:41:09+10:00March 17th, 2021|

Rawson RV, Adhikari C, Bierman C, Lo S, Shklovskaya E, Rozeman EA, Menzies AM, van Akkooi ACJ, Shannon KF, Gonzalez M M, Guminski AD, Tetzlaff MT, Stretch JR, Eriksson H, van Thienen JV, Wouters MW, Haanen JBAG, Klop WMC, Zuur CL, van Houdt WJ, Nieweg OE, Ch’ng S, Rizos H, Saw RPM, Spillane AJ, Wilmott JS, Blank CU, Long GV, van de Wiel BA, Scolyer RA. Ann Oncol. (Epub 17 March 2021)

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γδ T Cells in Merkel Cell Carcinomas Have a Proinflammatory Profile Prognostic of Patient Survival.

2025-05-29T15:18:22+10:00March 5th, 2021|

Gherardin NA, Waldeck K, Caneborg A, Martelotto LG, Balachander S, Zethoven M, Petrone PM, Pattison A, Wilmott JS, Quiñones-Parra SM, Rossello F, Posner A, Wong A, Weppler AM, Shannon KF, Hong A, Ferguson PM, Jakrot V, Raleigh J, Hatzimihalis A, Neeson PJ, Deleso P, Johnston M, Chua M, Becker JC, Sandhu S, McArthur GA, Gill AJ, Scolyer RA, Hicks RJ, Godfrey DI, Tothill RW. Cancer Immunol Res. (Epub 5 Mar 2021)

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Evolution of late-stage metastatic melanoma is dominated by aneuploidy and whole genome doubling.

2025-06-26T15:08:36+10:00March 4th, 2021|

Vergara IA, Mintoff CP, Sandhu S, McIntosh L, Young RJ, Wong SQ, Colebatch A, Cameron DL, Kwon JL, Wolfe R, Peng A, Ellul J, Dou X, Fedele C, Boyle S, Arnau GM, Raleigh J, Hatzimihalis A, Szeto P, Mooi J, Widmer DS, Cheng PF, Amann V, Dummer R, Hayward N, Wilmott J, Scolyer RA, Cho RJ, Bowtell D, Thorne H, Alsop K, Cordner S, Woodford N, Leditschke J, O’Brien P, Dawson SJ, McArthur GA, Mann GJ, Levesque MP, Papenfuss AT, Shackleton M. Nat Commun. (Epub 4 Mar 2021)

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Tumour gene expression signature in primary melanoma predicts long-term outcomes.

2025-06-26T11:24:33+10:00February 18th, 2021|

Garg M, Couturier DL, Nsengimana J, Fonseca NA, Wongchenko M, Yan Y, Lauss M, Jönsson GB, Newton-Bishop J, Parkinson C, Middleton MR, Bishop DT, McDonald S, Stefanos N, Tadross J, Vergara IA, Lo S, Newell F, Wilmott JS, Thompson JF, Long GV, Scolyer RA, Corrie P, Adams DJ, Brazma A, Rabbie R. Nat Commun. 2021 Feb 18;12(1):1137

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Pathological response and survival with neoadjuvant therapy in melanoma: a pooled analysis from the International Neoadjuvant Melanoma Consortium (INMC)

2022-06-09T10:58:09+10:00February 9th, 2021|

Alexander M. Menzies, Rodabe N. Amaria, Elisa A. Rozeman, Alexander C. Huang, Michael T. Tetzlaff, Bart A. van de Wiel, Serigne Lo, Ahmad A. Tarhini, Elizabeth M. Burton, Thomas E. Pennington, Robyn P. M. Saw, Xiaowei Xu, Giorgos C. Karakousis, Paolo A. Ascierto, Andrew J. Spillane, Alexander C. J. van Akkooi, Michael A. Davies, Tara C. Mitchell, Hussein A. Tawbi, Richard A. Scolyer, Jennifer A. Wargo, Christian U. Blank & Georgina V. Long.  Nat Med (2021).

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Survival and biomarker analyses from the OpACIN-neo and OpACIN neoadjuvant immunotherapy trials in stage III melanoma.

2025-06-23T15:35:09+10:00February 8th, 2021|

Rozeman EA, Hoefsmit EP, Reijers ILM, Saw RPM, Versluis JM, Krijgsman O, Dimitriadis P, Sikorska K, van de Wiel BA, Eriksson H, Gonzalez M, Torres Acosta A, Grijpink-Ongering LG, Shannon K, Haanen JBAG, Stretch J, Ch’ng S, Nieweg OE, Mallo HA, Adriaansz S, Kerkhoven RM, Cornelissen S, Broeks A, Klop WMC, Zuur CL, van Houdt WJ, Peeper DS, Spillane AJ, van Akkooi ACJ, Scolyer RA, Schumacher TNM, Menzies AM, Long GV, Blank CU. Nat Med. (Epub Feb 8 2021)

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